E2F5 antibody, N-term-多抗-深圳欣博盛生物科技有限公司

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E2F5 antibody, N-term

品牌：GeneTex

官网链接

说明书

折扣/货期

货号：GTX80623

规格：400μl

目录价：￥5600

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

E2F5 antibody, N-term

别名:

E2F transcription factor 5 , E2F-5

反应种属:

Human

宿主来源:

Rabbit

实验应用:

FCM, IHC-P, WB

同种型:

IgG

免疫原:

KLH conjugated synthetic peptide between 66-93 amino acids from the N-terminal region of human E2F5.

克隆性:

Polyclonal

克隆号:

纯化方式:

Protein A purified, followed by peptide affinity purification.

偶联:

Unconjugated

产品浓度:

Batch dependent (Please refer to the vial label for the specific concentration.)

保存温度:

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

运输温度:

4°C

预期分子量:

产品形式:

Liquid

存储溶液:

PBS, 0.09% Sodium azide.

生产商:

GeneTex

功能与背景:

The protein encoded by this gene is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionarily conserved domains that are present in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein is differentially phosphorylated and is expressed in a wide variety of human tissues. It has higher identity to E2F4 than to other family members. Both this protein and E2F4 interact with tumor suppressor proteins p130 and p107, but not with pRB. Alternative splicing results in multiple variants encoding different isoforms. [provided by RefSeq, Jul 2008]

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