| 货号:GTX628887 | 规格:100μl | 目录价:¥4000 |
| 货号:GTX628887-S | 规格:25μl | 目录价:¥1700 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
EGFR antibody [GT133]
别名:
epidermal growth factor receptor , ERBB , ERBB1 , HER1 , NISBD2 , PIG61 , mENA
产品描述:
EGFR antibody recognizes epidermal growth factor receptor (EGFR, also known as HER1 in humans), a receptor tyrosine kinase with a predicted molecular weight of 134 kDa. EGFR is involved in epithelial tissue development and homeostasis. It is also a driver of tumorigenesis. Upregulation or abnormal activation of EGFR is frequently found in glioblastomas, lung cancers, and breast cancers, among others.
反应种属:
Human
宿主来源:
Mouse
实验应用:
ICC/IF, IHC-P, IP, WB
靶标/特异性:
This antibody was raised against human EGFR Intracellular domain.This antibody does not cross-react with Her2/Erbb2 protein.,IP/MS validation is based on published data (PMID: 30377423).
同种型:
IgG2b
免疫原:
Recombinant protein encompassing a sequence within the Intracellular domain of human EGFR. The exact sequence is proprietary.
克隆性:
Monoclonal
克隆号:
GT133
纯化方式:
Affinity purified by Protein G.
偶联:
Unconjugated
产品浓度:
1 mg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
产品形式:
Liquid
存储溶液:
PBS, no preservatives.
生产商:
GeneTex
功能与背景:
The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. [provided by RefSeq]
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