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折扣/货期| 货号：GTX57580 | 规格：100μl | 目录价：￥5300 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
eIF2 alpha antibody [5E10]
别名:
eukaryotic translation initiation factor 2 subunit alpha , EIF2 , EIF2A , EIF2S1 , EIF2alpha , eIF2 alpha
反应种属:
Human, Mouse
宿主来源:
Mouse
实验应用:
ICC/IF, WB
同种型:
IgG2b
免疫原:
The clone 5E10 is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human EIF2S3 protein.
克隆性:
Monoclonal
克隆号:
50000000000
纯化方式:
Protein G Purified
偶联:
Unconjugated
产品浓度:
1 mg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
预期分子量:
36
产品形式:
Liquid
存储溶液:
PBS, 10% Glycerol, 0.02% Sodium azide.
生产商:
GeneTex
功能与背景:
The translation initiation factor EIF2 catalyzes the first regulated step of protein synthesis initiation, promoting the binding of the initiator tRNA to 40S ribosomal subunits. Binding occurs as a ternary complex of methionyl-tRNA, EIF2, and GTP. EIF2 is composed of 3 nonidentical subunits, the 36-kD EIF2-alpha subunit (EIF2S1), the 38-kD EIF2-beta subunit (EIF2S2; MIM 603908), and the 52-kD EIF2-gamma subunit (EIF2S3; MIM 300161). The rate of formation of the ternary complex is modulated by the phosphorylation state of EIF2-alpha (Ernst et al., 1987 [PubMed 2948954]).[supplied by OMIM, Feb 2010]
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