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折扣/货期| 货号：GTX635967 | 规格：100μl | 目录价：￥4000 |
| 货号：GTX635967-S | 规格：25μl | 目录价：￥1700 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
EpCAM antibody [GT25512]
别名:
epithelial cell adhesion molecule , DIAR5 , EGP-2 , EGP314 , EGP40 , ESA , HNPCC8 , KS1/4 , KSA , M4S1 , MIC18 , MK-1 , TACSTD1 , TROP1
产品描述:
EpCAM antibody recognizes epithelial cell adhesion molecule (EpCAM), a transmembrane glycoprotein with a predicted molecular weight of ~35 kDa. EpCAM is upregulated in epithelial cells during epithelial–mesenchymal transition (EMT) and is used as a diagnostic marker of many carcinomas and circulating tumor cells. Detection of EpCAM by immunohistochemistry is important for the diagnosis of certain epithelial malignancies.
反应种属:
Human
宿主来源:
Mouse
实验应用:
FCM, ICC/IF, IHC-P, WB
靶标/特异性:
This antibody was raised against human EpCAM Extracellular domain.,We do not recommend use of this product for Mouse.
同种型:
IgG2a
免疫原:
Recombinant protein encompassing a sequence within the Extracellular domain of human EpCAM. The exact sequence is proprietary.
克隆性:
Monoclonal
克隆号:
GT25512
纯化方式:
Affinity purified by Protein A.
偶联:
Unconjugated
产品浓度:
1 mg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
预期分子量:
35
产品形式:
Liquid
存储溶液:
PBS, 20% Glycerol, no preservatives.
生产商:
GeneTex
功能与背景:
This gene encodes a carcinoma-associated antigen and is a member of a family that includes at least two type I membrane proteins. This antigen is expressed on most normal epithelial cells and gastrointestinal carcinomas and functions as a homotypic calcium-independent cell adhesion molecule. The antigen is being used as a target for immunotherapy treatment of human carcinomas. Mutations in this gene result in congenital tufting enteropathy. [provided by RefSeq, Dec 2008]
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