| 货号:GTX02635 | 规格:100μg | 目录价:¥7000 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
Estrogen Receptor alpha antibody [ESR1/2299R]
别名:
estrogen receptor 1 , ER , ESR , ESRA , ESTRR , Era , NR3A1
反应种属:
Human
宿主来源:
Rabbit
实验应用:
IHC-P, WB
靶标/特异性:
This antibody is specific to ER alpha and shows minimal cross-reaction with other members of the family.
同种型:
IgG
免疫原:
Recombinant full-length human Estrogen Receptor alpha protein
克隆性:
Monoclonal
克隆号:
ESR1/2299R
纯化方式:
Protein A/G purified
偶联:
Unconjugated
产品浓度:
200 μg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.
运输温度:
4°C
预期分子量:
66
产品形式:
Liquid
存储溶液:
PBS, 0.05% BSA, 0.05% Sodium azide.
生产商:
GeneTex
功能与背景:
This gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative promoter usage and alternative splicing result in dozens of transcript variants, but the full-length nature of many of these variants has not been determined. [provided by RefSeq, Mar 2014]
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