| 货号:GTX79792 | 规格:500μg | 目录价:¥5300 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
Factor VII antibody
别名:
F7,SPCA,coagulation factor VII,Factor VII,FVII
反应种属:
Human
宿主来源:
Rabbit
实验应用:
ELISA, WB
同种型:
IgG
免疫原:
Full length native protein (purified) (Human).
克隆性:
Polyclonal
克隆号:
纯化方式:
Protein A purified
偶联:
Unconjugated
产品浓度:
10 mg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
预期分子量:
52
产品形式:
Liquid
存储溶液:
50mM Sodium Phosphate, 100mM NaCl, 1mM EDTA, no preservatives.
生产商:
GeneTex
功能与背景:
This gene encodes coagulation factor VII which is a vitamin K-dependent factor essential for hemostasis. This factor circulates in the blood in a zymogen form, and is converted to an active form by either factor IXa, factor Xa, factor XIIa, or thrombin by minor proteolysis. Upon activation of the factor VII, a heavy chain containing a catalytic domain and a light chain containing 2 EGF-like domains are generated, and two chains are held together by a disulfide bond. In the presence of factor III and calcium ions, the activated factor then further activates the coagulation cascade by converting factor IX to factor IXa and/or factor X to factor Xa. Defects in this gene can cause coagulopathy. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar proteolytic processing to generate mature polypeptides. [provided by RefSeq, Aug 2015]
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