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折扣/货期| 货号：GTX41198 | 规格：500μg | 目录价：￥8300 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Factor VII antibody [RFF-VII/1]
别名:
coagulation factor VII , SPCA
反应种属:
Human
宿主来源:
Mouse
实验应用:
ELISA, RIA, WB
靶标/特异性:
This antibody recognizes Factor VII. It may be used to detect Factor VII in immunoassays in combination with clone RFF-VII/2 (GTX41194, GTX41196) as a capture reagent.
同种型:
IgG1
免疫原:
Purified human factor VII.
克隆性:
Monoclonal
克隆号:
RFF-VII/1
纯化方式:
Protein G purified
偶联:
Unconjugated
产品浓度:
1.0 mg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
预期分子量:
52
产品形式:
Liquid
存储溶液:
PBS, 0.09% Sodium azide.
生产商:
GeneTex
功能与背景:
This gene encodes coagulation factor VII which is a vitamin K-dependent factor essential for hemostasis. This factor circulates in the blood in a zymogen form, and is converted to an active form by either factor IXa, factor Xa, factor XIIa, or thrombin by minor proteolysis. Upon activation of the factor VII, a heavy chain containing a catalytic domain and a light chain containing 2 EGF-like domains are generated, and two chains are held together by a disulfide bond. In the presence of factor III and calcium ions, the activated factor then further activates the coagulation cascade by converting factor IX to factor IXa and/or factor X to factor Xa. Defects in this gene can cause coagulopathy. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar proteolytic processing to generate mature polypeptides. [provided by RefSeq, Aug 2015]
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