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折扣/货期| 货号：GTX41178 | 规格：500μg | 目录价：￥8300 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Factor VIII antibody [RFF-VIIIC/8]
别名:
coagulation factor VIII , AHF , DXS1253E , F8B , F8C , FVIII , HEMA
反应种属:
Human, Pig
宿主来源:
Mouse
实验应用:
ELISA, RIA, WB
靶标/特异性:
This antibody recognizes an epitope towards the N-terminus of full-length Factor VIII. It also recognizes the 210kDa, 90kDa and 40kDa cleavage products. Clone RFF-VIIIC/8 does not cross-react with von Willebrand factor.
同种型:
IgG1
免疫原:
Affinity purified human Factor VIII.
克隆性:
Monoclonal
克隆号:
RFF-VIIIC/8
纯化方式:
Protein G purified
偶联:
Unconjugated
产品浓度:
1.0 mg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
预期分子量:
267
产品形式:
Liquid
存储溶液:
PBS, 0.09% Sodium azide.
生产商:
GeneTex
功能与背景:
This gene encodes coagulation factor VIII, which participates in the intrinsic pathway of blood coagulation; factor VIII is a cofactor for factor IXa which, in the presence of Ca+2 and phospholipids, converts factor X to the activated form Xa. This gene produces two alternatively spliced transcripts. Transcript variant 1 encodes a large glycoprotein, isoform a, which circulates in plasma and associates with von Willebrand factor in a noncovalent complex. This protein undergoes multiple cleavage events. Transcript variant 2 encodes a putative small protein, isoform b, which consists primarily of the phospholipid binding domain of factor VIIIc. This binding domain is essential for coagulant activity. Defects in this gene results in hemophilia A, a common recessive X-linked coagulation disorder. [provided by RefSeq, Jul 2008]
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