深圳欣博盛生物科技有限公司 a1

货号:GTX100612-S 规格:25μl 目录价:¥1700
货号:GTX100612 规格:100μl 目录价:¥4000
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
FADD antibody
别名:
Fas associated via death domain , GIG3 , MORT1
反应种属:
Human
宿主来源:
Rabbit
实验应用:
IHC-P, WB
同种型:
IgG
免疫原:
Recombinant protein encompassing a sequence within the center region of human FADD. The exact sequence is proprietary.
克隆性:
Polyclonal
克隆号:
纯化方式:
Purified by antigen-affinity chromatography.
偶联:
Unconjugated
产品浓度:
0.58 mg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
预期分子量:
23
产品形式:
Liquid
存储溶液:
PBS, 20% Glycerol, 0.025% ProClin 300.
生产商:
GeneTex
功能与背景:
The protein encoded by this gene is an adaptor molecule that interacts with various cell surface receptors and mediates cell apoptotic signals. Through its C-terminal death domain, this protein can be recruited by TNFRSF6/Fas-receptor, tumor necrosis factor receptor, TNFRSF25, and TNFSF10/TRAIL-receptor, and thus it participates in the death signaling initiated by these receptors. Interaction of this protein with the receptors unmasks the N-terminal effector domain of this protein, which allows it to recruit caspase-8, and thereby activate the cysteine protease cascade. Knockout studies in mice also suggest the importance of this protein in early T cell development. [provided by RefSeq]
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