FBXL11 antibody, Internal-多抗-深圳欣博盛生物科技有限公司

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FBXL11 antibody, Internal

品牌：GeneTex

官网链接

说明书

折扣/货期

货号：GTX82550

规格：400μl

目录价：￥5600

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

FBXL11 antibody, Internal

别名:

lysine demethylase 2A , CXXC8 , FBL11 , FBL7 , FBXL11 , JHDM1A , LILINA

反应种属:

Human

宿主来源:

Rabbit

实验应用:

IHC-P, WB

同种型:

IgG

免疫原:

KLH conjugated synthetic peptide between 500-527 amino acids from the Central region of human JHDM1a/FBXL11.

克隆性:

Polyclonal

克隆号:

纯化方式:

Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

偶联:

Unconjugated

产品浓度:

Batch dependent (Please refer to the vial label for the specific concentration.)

保存温度:

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

运输温度:

4°C

预期分子量:

133

产品形式:

Liquid

存储溶液:

PBS, 0.09% Sodium azide.

生产商:

GeneTex

功能与背景:

This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class and, in addition to an F-box, contains at least six highly degenerated leucine-rich repeats. This family member plays a role in epigenetic silencing. It nucleates at CpG islands and specifically demethylates both mono- and di-methylated lysine-36 of histone H3. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2012]

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