| 货号:GTX05209 | 规格:100μg | 目录价:¥6600 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
FBXO32 antibody
别名:
FBXO32,Fbox protein 32,Fbx32,MAFbx,Atrogin 1,MafBx,F-box protein 32
反应种属:
Human, Mouse
宿主来源:
Rabbit
实验应用:
ELISA, FCM, ICC/IF, WB
同种型:
IgG
免疫原:
E.coli-derived human FBXO32 recombinant protein (Position: Q6-F355)
克隆性:
Polyclonal
克隆号:
纯化方式:
Purified by antigen-affinity chromatography
偶联:
Unconjugated
产品浓度:
0.5 mg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
预期分子量:
42
产品形式:
Liquid
存储溶液:
4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na₂HPO₄, no preservatives.
生产商:
GeneTex
功能与背景:
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and contains an F-box domain. This protein is highly expressed during muscle atrophy, whereas mice deficient in this gene were found to be resistant to atrophy. This protein is thus a potential drug target for the treatment of muscle atrophy. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jun 2011]
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