| 货号:SIH-525-25MG | 规格:25 mg | 目录价:¥3225.6 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
Ferrostatin-1
别名:
Ethyl 3-amino-4-(cyclohexylamino)benzoate
产品描述:
Ferroptosis Inhibitor
保存温度:
-20ºC
运输温度:
Shipped Ambient
预期分子量:
262.4
产品形式:
Tan powder
产地:
加拿大
功能与背景:
Ferrostatin-1 inhibits ferroptosis (EC50=60 nM), an iron-dependent form of nonapoptotic cell death. It is especially potent of ferroptosis in cancer cells and glutamate-induced cell death in organotypic rat brain slices (1). It also blocks the cytotoxic effects of sorafenib in hepatocellular carcinoma cells (2), and inhibits oxidative lipid damage and cell death in diverse disease models (3). It has also been shown to mitigate rotenone-induced a-synuclein aggregation (4).
纯度:
>98% (TLC); NMR (Conforms)
来源:
Synthetic
CAS号:
347174-05-4
分子式:
C15H22N2O2
溶解度:
Soluble in DMSO (100 mg/ml) or ethanol (100 mg/ml)
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