深圳欣博盛生物科技有限公司 a1

FEZ1 antibody, Internal
货号:GTX89222 规格:100μg 目录价:¥5600
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
FEZ1 antibody, Internal
别名:
sirtuin 3 , SIR2L3
反应种属:
Human, Mouse, Rat
宿主来源:
Chicken
实验应用:
ELISA, WB
同种型:
IgY
免疫原:
SIRT3 antibody was raised against a 17 amino acid synthetic peptide near the center of human SIRT3.The immunogen is located within amino acids 180 - 230 of SIRT3.
克隆性:
Polyclonal
克隆号:
纯化方式:
Purified by antigen-affinity chromatography
偶联:
Unconjugated
产品浓度:
1 mg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
预期分子量:
44
产品形式:
Liquid
存储溶液:
PBS, 0.02% Sodium azide.
生产商:
GeneTex
功能与背景:
The Silent Information Regulator (SIR2) family of genes are highly conserved from prokaryotes to eukaryotes and have important functions in the regulation of metabolism, growth and differentiation, inflammation, cellular survival, as well as in senescence, lifespan extension and several age-related diseases. Sirtuins are NAD+-dependent histone/protein deacetylases (HDAC) and SIRT3 is the only sirtuin whose increased expression has been shown to correlate with an extended life span in humans. It is localized in the mitochondrial matrix, where it regulates the acetylation levels of metabolic enzymes, including acetyl coenzyme A synthetase 2. SIRT3 is stress-responsive and its increased expression protects myocytes from genotoxic and oxidative stress-mediated cell death.
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