FGFR1 (phospho Tyr766) + FGFR2 (phospho Tyr769) + FGFR3 (phospho Tyr760) antibody [HL3487]
官网链接
折扣/货期| 货号：GTX641372 | 规格：100μl | 目录价：￥4000 |
| 货号：GTX641372-S | 规格：25μl | 目录价：￥1700 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
FGFR1 (phospho Tyr766) + FGFR2 (phospho Tyr769) + FGFR3 (phospho Tyr760) antibody [HL3487]
别名:
fibroblast growth factor receptor 2 , BBDS , BEK , BFR-1 , CD332 , CEK3 , CFD1 , ECT1 , JWS , K-SAM , KGFR , TK14 , TK25
反应种属:
Human, Mouse
宿主来源:
Rabbit
实验应用:
WB
同种型:
IgG
免疫原:
Carrier-protein conjugated synthetic peptide surrounding phospho Tyr769 of human FGFR2. The exact sequence is proprietary.
克隆性:
Monoclonal
克隆号:
HL3487
纯化方式:
Affinity purified by Protein A.
偶联:
Unconjugated
产品浓度:
(Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
产品形式:
Liquid
存储溶液:
PBS, no preservatives.
生产商:
GeneTex
功能与背景:
The protein encoded by this gene is a member of the fibroblast growth factor receptor family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member is a high-affinity receptor for acidic, basic and/or keratinocyte growth factor, depending on the isoform. Mutations in this gene are associated with Crouzon syndrome, Pfeiffer syndrome, Craniosynostosis, Apert syndrome, Jackson-Weiss syndrome, Beare-Stevenson cutis gyrata syndrome, Saethre-Chotzen syndrome, and syndromic craniosynostosis. Multiple alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Jan 2009]
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