FKBP4 antibody-多抗-深圳欣博盛生物科技有限公司

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FKBP4 antibody

品牌：GeneTex

官网链接

说明书

折扣/货期

货号：GTX113437-S	规格：25μl	目录价：￥1700
货号：GTX113437	规格：100μl	目录价：￥4000

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

FKBP4 antibody

别名:

FKBP prolyl isomerase 4 , FKBP51 , FKBP52 , FKBP59 , HBI , Hsp56 , PPIase , p52

反应种属:

Human, Mouse, Rat

宿主来源:

Rabbit

实验应用:

ICC/IF, WB

同种型:

IgG

免疫原:

Recombinant protein encompassing a sequence within the center region of human FKBP4. The exact sequence is proprietary.

克隆性:

Polyclonal

克隆号:

纯化方式:

Purified by antigen-affinity chromatography.

偶联:

Unconjugated

产品浓度:

0.99 mg/ml (Please refer to the vial label for the specific concentration.)

保存温度:

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

运输温度:

4°C

产品形式:

Liquid

存储溶液:

0.1M Tris, 0.1M Glycine, 10% Glycerol, 0.01% Thimerosal.

生产商:

GeneTex

功能与背景:

The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds to the immunosuppressants FK506 and rapamycin. It has high structural and functional similarity to FK506-binding protein 1A (FKBP1A), but unlike FKBP1A, this protein does not have immunosuppressant activity when complexed with FK506. It interacts with interferon regulatory factor-4 and plays an important role in immunoregulatory gene expression in B and T lymphocytes. This encoded protein is known to associate with phytanoyl-CoA alpha-hydroxylase. It can also associate with two heat shock proteins (hsp90 and hsp70) and thus may play a role in the intracellular trafficking of hetero-oligomeric forms of the steroid hormone receptors. This protein correlates strongly with adeno-associated virus type 2 vectors (AAV) resulting in a significant increase in AAV-mediated transgene expression in human cell lines. Thus this encoded protein is thought to have important implications for the optimal use of AAV vectors in human gene therapy. The human genome contains several non-transcribed pseudogenes similar to this gene. [provided by RefSeq]

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