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折扣/货期| 货号：GTX80209 | 规格：100test | 目录价：￥4400 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
FLT3 antibody [BV10A4] (PE)
别名:
CD135 , FLK2 , FLT3 , STK1 , fms related tyrosine kinase 3
反应种属:
Human
宿主来源:
Mouse
实验应用:
FCM
靶标/特异性:
We do not recommend use of this product for Mouse.
同种型:
IgG1
免疫原:
BV-173 leukemic cell line
克隆性:
Monoclonal
克隆号:
BV10A4
纯化方式:
Purified by size-exclusion chromatography
偶联:
PE
产品浓度:
Batch dependent (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE. Protect from light.
运输温度:
4°C
产品形式:
Liquid
存储溶液:
PBS, 15mM Sodium azide.
生产商:
GeneTex
功能与背景:
This gene encodes a class III receptor tyrosine kinase that regulates hematopoiesis. This receptor is activated by binding of the fms-related tyrosine kinase 3 ligand to the extracellular domain, which induces homodimer formation in the plasma membrane leading to autophosphorylation of the receptor. The activated receptor kinase subsequently phosphorylates and activates multiple cytoplasmic effector molecules in pathways involved in apoptosis, proliferation, and differentiation of hematopoietic cells in bone marrow. Mutations that result in the constitutive activation of this receptor result in acute myeloid leukemia and acute lymphoblastic leukemia. [provided by RefSeq, Jan 2015]
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