官网链接
折扣/货期| 货号：GTX84485 | 规格：100μl | 目录价：￥7600 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
FOXA2 antibody [3C10]
别名:
forkhead box A2 , HNF3B , TCF3B
反应种属:
Human, Mouse
宿主来源:
Mouse
实验应用:
FCM, ICC/IF, IHC-P, WB
同种型:
IgG1
免疫原:
Recombinant protein expressed in E.coli corresponding to amino acids 300-458 of human FOXA2
克隆性:
Monoclonal
克隆号:
3C10
纯化方式:
Purified by affinity chromatography
偶联:
Unconjugated
产品浓度:
1 mg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
预期分子量:
48
产品形式:
Liquid
存储溶液:
PBS, 1% BSA, 50% Glycerol, 0.02% Sodium azide.
生产商:
GeneTex
功能与背景:
Transcription factor that is involved in embryonic development, establishment of tissue-specific gene expression and regulation of gene expression in differentiated tissues. Is thought to act as a 'pioneer' factor opening the compacted chromatin for other proteins through interactions with nucleosomal core histones and thereby replacing linker histones at target enhancer and/or promoter sites. Binds DNA with the consensus sequence 5'-[AC]A[AT]T[AG]TT[GT][AG][CT]T[CT]-3' (By similarity). In embryonic development is required for notochord formation. Involved in the development of multiple endoderm-derived organ systems such as the liver, pancreas and lungs | FOXA1 and FOXA2 seem to have at least in part redundant roles. Originally discribed as a transcription activator for a number of liver genes such as AFP, albumin, tyrosine aminotransferase, PEPCK, etc. Interacts with the cis-acting regulatory regions of these genes. Involved in glucose homeostasis | regulates the expression of genes important for glucose sensing in pancreatic beta-cells and glucose homeostasis. Involved in regulation of fat metabolism. Binds to fibrinogen beta promoter and is involved in IL6-induced fibrinogen beta transcriptional activation.
您可能感兴趣的产品
Sialosyl-Tn antigen antibody (Prediluted for IHC)
货号：75R-1060
Insulin antibody (Prediluted for IHC)
货号：75R-1058
MPO antibody (Prediluted for IHC)
货号：75R-1050
Luteinizing Hormone antibody (Prediluted for IHC)
货号：75R-1049
Desmin antibody (Prediluted for IHC)
货号：75R-1048
Transferrin antibody (Prediluted for IHC)
货号：75R-1047
alpha 1 Antitrypsin antibody (Prediluted for IHC)
货号：75R-1044
Lysozyme antibody (Prediluted for IHC)
货号：75R-1043
促销活动
精品推荐
复制QQ号成功，请打开QQ后添加好友进行咨询