FOXO4 antibody-多抗-深圳欣博盛生物科技有限公司

首页产品中心多抗

FOXO4 antibody

品牌：GeneTex

官网链接

说明书

折扣/货期

货号：GTX12075

规格：50μl

目录价：￥6600

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

FOXO4 antibody

别名:

forkhead box O4 , AFX , AFX1 , MLLT7

反应种属:

Human

宿主来源:

Rabbit

实验应用:

ICC/IF, IP, WB

同种型:

IgG

免疫原:

synthetic peptide corresponding to the C-terminus of human AFX (amino acids 451-466) with N-terminally added lysine) conjugated to KLH.

克隆性:

Polyclonal

克隆号:

纯化方式:

Purified by affinity chromatography

偶联:

Unconjugated

产品浓度:

Batch dependent (Please refer to the vial label for the specific concentration.)

保存温度:

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

运输温度:

4°C

产品形式:

Liquid

存储溶液:

PBS, 1% BSA, 15mM Sodium azide.

生产商:

GeneTex

功能与背景:

The forkhead family of transcription factors is involved in tumorigenesis in rhabdomyosarcoma and acute leukemias. Within the family, three members (FKHR, AFX and FKHRL1) have sequence similarity to the nematode homolog Daf 16, recently shown to mediate signaling via a pathway involving IGFR1, P13-K and Akt. There are three potential Akt phosphorylation sites on the FKHR proteins. One site, FKHR Ser256 is found in the Forkhead domain and the other two are outside this domain. Recent studies show that phosphorylation of FKHR family members by Akt promotes cell survival. Phosphorylation regulates FKHR nuclear translocation and target gene transcription. Insulin also stimulates FKHR phosphorylation at Ser253.

您可能感兴趣的产品

sPLA2 (human Type IIA) Polyclonal Antibody - Purified IgG

货号：45805

PAD3 Polyclonal Antibody

货号：33913

Growth Hormone (rat) Polyclonal Antibody for IHC

货号：C03904.25 µl

Goat Anti-ImmunoglobulinG (mouse) Polyclonal Antibody

货号：C03757.10 ml

Goat Anti-ImmunoglobulinG (rat) Polyclonal Antibody

货号：C03756.10 ml

Goat Anti-ImmunoglobulinG (guinea pig) Polyclonal Antibody