GAD2 Antibody / GAD65-单抗-深圳欣博盛生物科技有限公司

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GAD2 Antibody / GAD65

品牌：NSJ Bio

官网链接

说明书

折扣/货期

货号：V4077SAF-100UG

规格：100 ug

目录价：￥6414.1

产品详情

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产品名称:

GAD2 Antibody / GAD65

产品描述:

This mAb recognizes a protein of 65kDa, which is identified as glutamic acid decarboxylase 2 (GDA2). It is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. There are two forms of glutamic acid decarboxylases (GADs) that are found in the brain: GAD2 (also known as GAD65) and GAD1 (also known as GAD67). GAD1 and GAD2 are members of the group II decarboxylase family of proteins and are responsible for catalyzing the rate-limiting step in the production of GABA (Gamma-aminobutyric acid) from L-glutamic acid. Although both GAD s are found in the brain, GAD2 localizes to synaptic vesicle membranes in nerve terminals, while GAD1 is distributed throughout the cell. A pathogenic role for GAD2 is identified in the human pancreas since it has been identified as an autoantibody and an auto-reactive T cell target in insulin-dependent diabetes.

反应种属:

Human

宿主来源:

Rabbit

实验应用:

IHC-P

同种型:

Rabbit IgG, kappa

免疫原:

A recombinant human GAD2/GAD65 protein fragment (within amino acids 1-200) was used as the immunogen for the GAD2 antibody.

克隆性:

Recombinant Rabbit Monoclonal