gamma Adducin antibody-多抗-深圳欣博盛生物科技有限公司

首页产品中心多抗

gamma Adducin antibody

品牌：GeneTex

官网链接

说明书

折扣/货期

货号：GTX54942

规格：100μl

目录价：￥4700

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

gamma Adducin antibody

别名:

adducin 3 , ADDL , CPSQ3

反应种属:

Human, Mouse, Rat

宿主来源:

Rabbit

实验应用:

同种型:

IgG

免疫原:

KLH-conjugated synthetic peptide encompassing a sequence within the center region of gamma Adducin. The exact sequence is proprietary.

克隆性:

Polyclonal

克隆号:

纯化方式:

Purified by antigen-affinity chromatography

偶联:

Unconjugated

产品浓度:

Batch dependent (Please refer to the vial label for the specific concentration.)

保存温度:

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

运输温度:

4°C

产品形式:

Liquid

存储溶液:

0.42% Potassium Phosphate, 0.87% NaCl, 30% Glycerol, 0.01% Sodium azide.

生产商:

GeneTex

功能与背景:

Adducins are heteromeric proteins composed of different subunits referred to as adducin alpha, beta and gamma. The three subunits are encoded by distinct genes and belong to a family of membrane skeletal proteins involved in the assembly of spectrin-actin network in erythrocytes and at sites of cell-cell contact in epithelial tissues. While adducins alpha and gamma are ubiquitously expressed, the expression of adducin beta is restricted to brain and hematopoietic tissues. Adducin, originally purified from human erythrocytes, was found to be a heterodimer of adducins alpha and beta. Polymorphisms resulting in amino acid substitutions in these two subunits have been associated with the regulation of blood pressure in an animal model of hypertension. Heterodimers consisting of alpha and gamma subunits have also been described. Structurally, each subunit is comprised of two distinct domains. The amino-terminal region is protease resistant and globular in shape, while the carboxy-terminal region is protease sensitive. The latter contains multiple phosphorylation sites for protein kinase C, the binding site for calmodulin, and is required for association with spectrin and actin. Alternatively spliced adducin gamma transcripts encoding different isoforms have been described. The functions of the different isoforms are not known. [provided by RefSeq, Jul 2008]

您可能感兴趣的产品

Lyve-1 (human) antibody

货号：RLT-102-PABI50

Anti-Collagenase (Clostridium histolyticum), polyclonal antibody from sheep

货号：NB-58050-01

Anti-Collagenase (Clostridium histolyticum) HRP, polyclonal antibody from sheep