Geminin antibody-多抗-深圳欣博盛生物科技有限公司

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Geminin antibody

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品牌：GeneTex

官网链接

说明书

折扣/货期

货号：GTX12147

规格：200μl

目录价：￥5300

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

Geminin antibody

别名:

geminin DNA replication inhibitor , Gem , MGORS6

反应种属:

Human

宿主来源:

Rabbit

实验应用:

ICC/IF, IHC-P, WB

靶标/特异性:

This antibody detects a band representing Geminin by Western blot at 33kD on 293T cell lysate, this band can be blocked by the immunising peptide. It also detects a band at about 45kD that is not blocked by the immunising peptide and is thought to be non-specific.

同种型:

IgG

免疫原:

Synthetic peptide: SSENKNLGGVTQES-C conjugated to KLH, corresponding to amino acids 72-85 of Human Geminin.

克隆性:

Polyclonal

克隆号:

纯化方式:

Immunogen affinity purified

偶联:

Unconjugated

产品浓度:

0.1 mg/ml (Please refer to the vial label for the specific concentration.)

保存温度:

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

运输温度:

4°C

预期分子量:

产品形式:

Liquid

存储溶液:

PBS, 1% BSA, 0.02% Sodium azide.

生产商:

GeneTex

功能与背景:

This gene encodes a protein that plays a critical role in cell cycle regulation. The encoded protein inhibits DNA replication by binding to DNA replication factor Cdt1, preventing the incorporation of minichromosome maintenance proteins into the pre-replication complex. The encoded protein is expressed during the S and G2 phases of the cell cycle and is degraded by the anaphase-promoting complex during the metaphase-anaphase transition. Increased expression of this gene may play a role in several malignancies including colon, rectal and breast cancer. Alternatively spliced transcript variants have been observed for this gene, and two pseudogenes of this gene are located on the short arm of chromosome 16. [provided by RefSeq, Oct 2011]

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