GIT2 antibody [N1N3]-多抗-深圳欣博盛生物科技有限公司

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GIT2 antibody [N1N3]

品牌：GeneTex

官网链接

说明书

折扣/货期

货号：GTX116427	规格：100μl	目录价：￥4000
货号：GTX116427-S	规格：25μl	目录价：￥1700

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

GIT2 antibody [N1N3]

别名:

GIT ArfGAP 2 , CAT-2 , CAT2 , PKL

反应种属:

Human, Mouse

宿主来源:

Rabbit

实验应用:

ICC/IF, IHC-Fr, WB

同种型:

IgG

免疫原:

Recombinant protein encompassing a sequence within the center region of human GIT2. The exact sequence is proprietary.

克隆性:

Polyclonal

克隆号:

纯化方式:

Purified by antigen-affinity chromatography.

偶联:

Unconjugated

产品浓度:

0.81 mg/ml (Please refer to the vial label for the specific concentration.)

保存温度:

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

运输温度:

4°C

产品形式:

Liquid

存储溶液:

0.1M Tris, 0.1M Glycine, 20% Glycerol, 0.01% Thimerosal.

生产商:

GeneTex

功能与背景:

This gene encodes a member of the GIT protein family, which interact with G protein-coupled receptor kinases and possess ADP-ribosylation factor (ARF) GTPase-activating protein (GAP) activity. GIT proteins traffic between cytoplasmic complexes, focal adhesions, and the cell periphery, and interact with Pak interacting exchange factor beta (PIX) to form large oligomeric complexes that transiently recruit other proteins. GIT proteins regulate cytoskeletal dynamics and participate in receptor internalization and membrane trafficking. This gene has been shown to repress lamellipodial extension and focal adhesion turnover, and is thought to regulate cell motility. This gene undergoes extensive alternative splicing to generate multiple isoforms, but the full-length nature of some of these variants has not been determined. The various isoforms have functional differences, with respect to ARF GAP activity and to G protein-coupled receptor kinase 2 binding. [provided by RefSeq]

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