| 货号:GTX638352 | 规格:100μl | 目录价:¥4000 |
| 货号:GTX638352-S | 规格:25μl | 目录价:¥1700 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
GLP1R antibody [HL2297]
别名:
glucagon like peptide 1 receptor , GLP-1 , GLP-1-R , GLP-1R
反应种属:
Human, Mouse, Rat
宿主来源:
Rabbit
实验应用:
IHC-P
靶标/特异性:
This antibody was raised against human GLP1R Extracellular domain.
同种型:
IgG
免疫原:
Synthetic peptide encompassing a sequence within the Extracellular domain human of GLP1R. The exact sequence is proprietary.
克隆性:
Monoclonal
克隆号:
HL2297
纯化方式:
Affinity purified by Protein A.
偶联:
Unconjugated
产品浓度:
2 mg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
产品形式:
Liquid
存储溶液:
PBS, no preservatives.
生产商:
GeneTex
功能与背景:
This gene encodes a 7-transmembrane protein that functions as a receptor for glucagon-like peptide 1 (GLP-1) hormone, which stimulates glucose-induced insulin secretion. This receptor, which functions at the cell surface, becomes internalized in response to GLP-1 and GLP-1 analogs, and it plays an important role in the signaling cascades leading to insulin secretion. It also displays neuroprotective effects in animal models. Polymorphisms in this gene are associated with diabetes. The protein is an important drug target for the treatment of type 2 diabetes and stroke. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Apr 2016]
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