| 货号:GTX82705 | 规格:100μl | 目录价:¥6200 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
Glutathione S-transferase kappa 1 antibody
反应种属:
Human, Mouse
宿主来源:
Rabbit
实验应用:
ICC/IF, IHC, WB
同种型:
IgG
免疫原:
Full length recombinant mouse Glutathione S-transferase kappa 1 protein
克隆性:
Polyclonal
克隆号:
纯化方式:
Serum
偶联:
Unconjugated
产品浓度:
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
预期分子量:
25
产品形式:
Liquid
存储溶液:
Serum, 40% Glycerol, no preservatives.
生产商:
GeneTex
功能与背景:
Disulfide-bond-A oxidoreductase-like protein (DsbA-L, previously named as GST Kappa) is an adiponectin-interacting protein. DsbA-L is highly expressed in adipose tissue, and its expression level is negatively correlated with obesity in mice and humans. DsbA-L expression in 3T3-L1 adipocytes is stimulated by the insulin sensitizer rosiglitazone and inhibited by the inflammatory cytokine TNFalpha. Polymorphism of DsbA-L gene has recently been implicated in insulin secretion and body fat distribution. Overexpression of DsbA-L promotes adiponectin multimerization while suppressing DsbA-L expression by RNAi markedly and selectively reduces adiponectin levels and secretion in 3T3-L1 adipocytes. Recent studies identify DsbA-L as a key regulator for adiponectin biosynthesis.
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