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折扣/货期| 货号：57-993 | 规格：400 ul | 目录价：￥8687.25 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
WWOX Antibody
别名:
WW domain-containing oxidoreductase, 111-, Fragile site FRA16D oxidoreductase, WWOX, FOR, WOX1
反应种属:
Mouse
宿主来源:
Rabbit
实验应用:
WB
同种型:
Rabbit Ig
克隆性:
Polyclonal
纯化方式:
This antibody is purified through a protein A column, followed by peptide affinity purification.
偶联:
Unconjugated
产品浓度:
batch dependent
保存温度:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
运输温度:
Blue Ice
产品形式:
Liquid
存储溶液:
Supplied in PBS with 0.09% (W/V) sodium azide.
产地:
美国
生产商:
Prosci
功能与背景:
WW domain-containing proteins are found in all eukaryotes
and play an important role in the regulation of a wide variety of
cellular functions such as protein degradation, transcription, and
RNA splicing. This gene encodes a protein which contains 2 WW
domains and a short-chain dehydrogenase/reductase domain (SRD). The
highest normal expression of this gene is detected in hormonally
regulated tissues such as testis, ovary, and prostate. This
expression pattern and the presence of an SRD domain suggest a role
for this gene in steroid metabolism. The encoded protein is more
than 90% identical to the mouse protein, which is an essential
mediator of tumor necrosis factor-alpha-induced apoptosis,
suggesting a similar, important role in apoptosis for the human
protein. In addition, there is evidence that this gene behaves as a
suppressor of tumor growth. Alternative splicing of this gene
generates transcript variants that encode different isoforms.
Accession #:
Q9NZC7
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