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折扣/货期| 货号：GTX639924-S | 规格：100μl | 目录价：￥3300 |
| 货号：GTX639924 | 规格：500μl | 目录价：￥6500 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
GPX2 antibody [HMV301] HistoMAX™
别名:
glutathione peroxidase 2 ,GI-GPx ,GPRP ,GPRP-2 ,GPx-2 ,GPx-GI ,GSHPX-GI ,GSHPx-2
产品描述:
This antibody was validated on 76 different Normal Tissues by IHC-P.
反应种属:
Human
宿主来源:
Rabbit
实验应用:
IHC-P
靶标/特异性:
<b>Highly recommended for IHC-P in human tissues.</b>
同种型:
IgG
免疫原:
Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human GPX2. The exact sequence is proprietary.
克隆性:
Monoclonal
克隆号:
HMV301
纯化方式:
Affinity purified by Protein A.
偶联:
Unconjugated
产品浓度:
0.36 mg/ml
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
产品形式:
Liquid
存储溶液:
PBS, 2% BSA, 0.025% ProClin 300.
生产商:
GeneTex
功能与背景:
The protein encoded by this gene belongs to the glutathione peroxidase family, members of which catalyze the reduction of organic hydroperoxides and hydrogen peroxide (H2O2) by glutathione, and thereby protect cells against oxidative damage. Several isozymes of this gene family exist in vertebrates, which vary in cellular location and substrate specificity. This isozyme is predominantly expressed in the gastrointestinal tract (also in liver in human), is localized in the cytoplasm, and whose preferred substrate is hydrogen peroxide. Overexpression of this gene is associated with increased differentiation and proliferation in colorectal cancer. This isozyme is also a selenoprotein, containing the rare amino acid selenocysteine (Sec) at its active site. Sec is encoded by the UGA codon, which normally signals translation termination. The 3' UTRs of selenoprotein mRNAs contain a conserved stem-loop structure, designated the Sec insertion sequence (SECIS) element, that is necessary for the recognition of UGA as a Sec codon, rather than as a stop signal. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2016]
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