| 货号:GTX52344 | 规格:100μg | 目录价:¥5300 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
GRF1 (phospho Tyr1105) antibody
别名:
Rho GTPase activating protein 35 , GRF-1 , GRLF1 , P190-A , P190A , p190ARhoGAP , p190RhoGAP
反应种属:
Human, Mouse, Rat
宿主来源:
Rabbit
实验应用:
ICC/IF, IHC-P, WB
靶标/特异性:
GRLF1
同种型:
IgG
免疫原:
A synthesized peptide derived from human GRF1 around the phosphorylation site of Tyr1105
克隆性:
Polyclonal
克隆号:
纯化方式:
Antigen affinity purification
偶联:
Unconjugated
产品浓度:
1 mg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
预期分子量:
171
产品形式:
Liquid
存储溶液:
PBS, 150mM NaCl, 50% Glycerol, 0.02% Sodium azide.
生产商:
GeneTex
功能与背景:
The human glucocorticoid receptor DNA binding factor, which associates with the promoter region of the glucocorticoid receptor gene (hGR gene), is a repressor of glucocorticoid receptor transcription. The amino acid sequence deduced from the cDNA sequences show the presence of three sequence motifs characteristic of a zinc finger and one motif suggestive of a leucine zipper in which 1 cysteine is found instead of all leucines. The GRLF1 enhances the homologous down-regulation of wild-type hGR gene expression. Biochemical analysis suggests that GRLF1 interaction is sequence specific and that transcriptional efficacy of GRLF1 is regulated through its interaction with specific sequence motif. The level of expression is regulated by glucocorticoids. [provided by RefSeq, Jul 2008]
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