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折扣/货期| 货号：SMC-232D-APC | 规格：100 µg | 目录价：￥4914 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
GRP170 Antibody: APC
别名:
ORP150 Antibody, HSP12A Antibody, Hypoxia up regulated 1 Antibody, Orp150 Antibody, Glucose regulated Antibody 170 Antibody, 150kDa oxygen regulated Antibody Antibody, 150 kDa oxygen regulated protein antibody, 150 kDa oxygen-regulated protein antibody, 170 kDa glucose regulated protein antibody, 170 kDa glucose-regulated protein antibody, DKFZp686N08236 antibody, FLJ94899 antibody, FLJ97572 antibody, glucose regulated protein 170 antibody, Grp 170 antibody, GRP-170 antibody, Grp170 antibody, HSP 12A antibody, HSP12A antibody, Hyou1 antibody, HYOU1_HUMAN antibody, Hypoxia up regulated 1 antibody, hypoxia up-regulated 1 precursor antibody, Hypoxia up-regulated protein 1 antibody, Hypoxia upregulated 1 antibody, Orp 150 antibody, ORP-150 antibody, Orp150 antibody, oxygen regulated protein (150kD) antibody
产品描述:
Mouse Anti-Human GRP170 Monoclonal IgG2bK
反应种属:
Human | Mouse | Rat
宿主来源:
Mouse
实验应用:
WB | ICC/IF
靶标/特异性:
Detects ~170kDa.
同种型:
IgG2b
推荐稀释度:
WB (1:1000), ICC/IF (1:100); optimal dilutions for assays should be determined by the user.
免疫原:
Recombinant Full length Human GRP170 Protein
免疫原种属:
Human
克隆性:
Monoclonal
克隆号:
6E3-2C3
纯化方式:
Protein G Purified
偶联:
APC
产品浓度:
1 mg/ml
保存温度:
Conjugated antibodies should be stored according to the product label
运输温度:
Blue Ice or 4ºC
存储溶液:
PBS pH7.4, 50% glycerol, 0.1% sodium azide *Storage buffer may change when conjugated
产地:
加拿大
功能与背景:
GRP170, also known as ORP150, is the largest member of glucose-regulated Antibodys, and acts as a human chaperone Antibody. It is thought to play an important role in Antibody folding and secretion in the ER. Suppression of the Antibody is associated with accelerated apoptosis, therefore having an important cryoprotective role in hypoxia-induced cellular pertubation. This cryopotective role has led to an anti-tumor immune response, which will hopefully lead to therapeutic immunizations against cancers (1). GRP170 has also been shown to bind with dendritic cells and provide the danger signals to induce anti-tumor immune responses (2).
Accession #:
NP_006389.3
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