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折扣/货期| 货号：GTX89202 | 规格：100μg | 目录价：￥5600 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
HAP1 antibody, Internal
别名:
huntingtin associated protein 1 , HAP2 , HIP5 , HLP , hHLP1
反应种属:
Human
宿主来源:
Goat
实验应用:
IHC-P, WB
靶标/特异性:
This antibody is expected to recognize all reported isoforms (NP_003940.1, NP_817084.1)
同种型:
IgG
免疫原:
Peptide with sequence C-RYDFRYSEDREQ, from the internal region of the protein sequence according to NP_003940.2; NP_817084.1.
克隆性:
Polyclonal
克隆号:
纯化方式:
Purified by ammonium sulphate precipitation followed by antigen affinity chromatography
偶联:
Unconjugated
产品浓度:
0.50 mg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
预期分子量:
76
产品形式:
Liquid
存储溶液:
TBS, 0.5% BSA, 0.02% Sodium azide.
生产商:
GeneTex
功能与背景:
Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein that interacts with huntingtin, with two cytoskeletal proteins (dynactin and pericentriolar autoantigen protein 1), and with a hepatocyte growth factor-regulated tyrosine kinase substrate. The interactions with cytoskeletal proteins and a kinase substrate suggest a role for this protein in vesicular trafficking or organelle transport. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]
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