官网链接
折扣/货期| 货号：GTX27028 | 规格：50μl | 目录价：￥5000 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
HDAC1 antibody
别名:
histone deacetylase 1 , GON-10 , HD1 , KDAC1 , RPD3 , RPD3L1
反应种属:
Human, Mouse, Rat
宿主来源:
Rabbit
实验应用:
ICC/IF, IHC-P, IP, WB
靶标/特异性:
Solution in 0.01 M phosphate bufffered saline, pH 7.4, containing 15 mM sodium azide.
同种型:
IgG
免疫原:
synthetic peptide corresponding to amino acids 466-482 of human and mouse HDAC1.
克隆性:
Polyclonal
克隆号:
纯化方式:
IgG fraction
偶联:
Unconjugated
产品浓度:
Batch dependent (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
预期分子量:
55
产品形式:
Liquid
存储溶液:
PBS, 15mM Sodium azide.
生产商:
GeneTex
功能与背景:
Reversible acetylation of highly conserved lysine residues in N-terminal tail domains of core histones plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone acetylation is a dynamic process determined by the net activities of histone acetyltransferases (HATs) and the competing enzymes histone deacetylases (HDACs) (ref 3). Histone deacetylases activities were often, but not always, associated with transcriptional repression and nucleosomal condensations (ref 6,7). Recruitment of the multiprotein complexes to promoter sites occurs by many sequence specific DNA-binding proteins such as unliganded nuclear hormone receptors, DP1-E2F, YY1 and Rb family of transcription factors, transcriptional repressors and tumor suppressors (e.g. BRCA1). Aberrant recruitment of HDACs by certain oncoproteins may occur in certain neoplastic diseases.(ref 11)
您可能感兴趣的产品
ApoB Polyclonal Antibody
货号：44650
WDR24 antibody
货号：GTX133576
Avian Influenza A virus H9N2 HA (Hemagglutinin) antibody
货号：GTX127306
Influenza A virus M2 (matrix protein) antibody
货号：GTX125951
Acta2 antibody
货号：GTX124505
MCTS1 antibody [N1C3]
货号：GTX117793
MAFG antibody
货号：GTX114541
Golgin 97 antibody [C2C3], C-term
货号：GTX114445
促销活动
精品推荐
复制QQ号成功，请打开QQ后添加好友进行咨询