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折扣/货期| 货号：SMC-175D-HRP | 规格：100 µg | 目录价：￥4901.4 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
HDEL Antibody: HRP
别名:
H-D-E-L (his-asp-glu-leu) Antibody, endoplasmic reticulum Antibody, luminal ER protein retention Antibody, KDELR1 Antibody, Endoplasmic reticulum retention signal Antibody
产品描述:
Mouse Anti-Yeast HDEL Monoclonal IgG2b
反应种属:
Fruit Fly (Drosophila melanogaster) | Yeast | Yeast (Saccharomyces cerevisiae) | Plant | Barnyard Grass (Echinochloa) | Beet (Beta vulgaris) | Cotton (Gossypium) | Mung Bean (Vigna radiata) | Grass (Sorghum) | Wheat (Triticum spp.)
宿主来源:
Mouse
实验应用:
WB | ICC/IF
靶标/特异性:
Detects ~78kDa.
同种型:
IgG2b
推荐稀释度:
WB (1:1000), ICC/IF (1:100); optimal dilutions for assays should be determined by the user.
免疫原:
Raised against a synthetic HDEL peptide corresponding to the C-terminus of yeast Bip
免疫原种属:
Yeast
克隆性:
Monoclonal
克隆号:
20000000
纯化方式:
Protein G Purified
偶联:
HRP
产品浓度:
1 mg/ml
保存温度:
Conjugated antibodies should be stored according to the product label
运输温度:
Blue Ice or 4ºC
存储溶液:
PBS pH7.4, 50% glycerol, 0.09% sodium azide *Storage buffer may change when conjugated
产地:
加拿大
功能与背景:
HSP 70 family comprises four highly conserved proteins, HSP 70, HSC 70, GRP 75 and GRP 78, which serve a variety of roles. They act as molecular chaperones, facilitating the assembly of multi-protein complexes; participate in the translocation of polypeptides across cell membranes and to the nucleus; and aid in the proper folding of nascent polypeptide chains (1, 2). GRP 78 is localized in the endoplasmic reticulum (ER), where it receives imported secretory proteins and is involved in the folding and translocation of nascent peptide chains (2). Sorting of these proteins is dependent on a C-terminal tetrapeptide signal, usually KDEL in animal cells, and HDEL in S.cerevisiae (3). The 2E7 clone recognizes the C-terminal peptide HDEL, a common version of the endoplasmic reticulum retention signal found in yeast, plant, nematode and other ER proteins. 2E7 specifically stains HDEL proteins in barnyard grass, beet, cotton, mung bean, sorghum and wheat (4).
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