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折扣/货期| 货号：GTX84310 | 规格：100μl | 目录价：￥7300 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
HIPPI antibody [4F6]
别名:
intraflagellar transport 57 , ESRRBL1 , HIPPI , MHS4R2 , OFD18
反应种属:
Human, Monkey, Mouse, Rat
宿主来源:
Mouse
实验应用:
ICC/IF, IHC-P, WB
同种型:
IgG1
免疫原:
Full length human recombinant protein of human IFT57(NP_060480) produced in HEK293T cell.
克隆性:
Monoclonal
克隆号:
4F6
纯化方式:
Purified by affinity chromatography
偶联:
Unconjugated
产品浓度:
1 mg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
预期分子量:
49
产品形式:
Liquid
存储溶液:
PBS, 1% BSA, 50% Glycerol, 0.02% Sodium azide.
生产商:
GeneTex
功能与背景:
Required for the formation of cilia. Plays an indirect role in sonic hedgehog signaling, cilia being required for all activity of the hedgehog pathway (By similarity). Has pro-apoptotic function via its interaction with HIP1, leading to recruit caspase-8 (CASP8) and trigger apoptosis. Has the ability to bind DNA sequence motif 5'-AAAGACATG-3' present in the promoter of caspase genes such as CASP1, CASP8 and CASP10, suggesting that it may act as a transcription regulator | however the relevance of such function remains unclear.
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