Histone H2A.vS137ph (phospho Ser137) antibody-多抗-深圳欣博盛生物科技有限公司

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Histone H2A.vS137ph (phospho Ser137) antibody

品牌：GeneTex

官网链接

说明书

折扣/货期

货号：GTX48733

规格：50μg

目录价：￥5300

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

Histone H2A.vS137ph (phospho Ser137) antibody

别名:

Histone H2A variant , 5499 , CG5499 , Dmel\CG5499 , H2A , H2A.F/Z , H2A.V , H2A.X , H2A.Z , H2AV , H2AV_DROM , H2AX , H2AZ , H2Av , H2AvD , H2a.V , H2av , H2avD , HIS , HIS2AV , HIS2AVD , His , His2 , His2A , His2AV , His2AvD , HisH2Av , Hist , Hist2av , gamma-H2AV , gamma-H2Av , gamma-HIS2AV , gamma-His2Av , gammaH2AV , gammaH2Av , h2AvD , his , his2Av , l(3)05146 , l(3)810 , l(3)97Dd , l(3)L1602

反应种属:

Drosophila

宿主来源:

Rabbit

实验应用:

ChIP assay, ELISA, EM, ICC/IF, IHC-P, Multiplexing, WB

靶标/特异性:

Reactivity occurs against Drosophila H2AvD pS137 protein and the antibody is specific for the phosphorylated form of the protein. Reactivity with non-phosphorylated Drosophila H2AvD is minimal by ELISA.

同种型:

IgG

免疫原:

Synthetic peptide corresponding to the C-Terminal region near amino acids 125-141 of Drosophila melanogaster (fruit fly) H2AvD protein.

克隆性:

Polyclonal

克隆号:

纯化方式:

Purified by antigen-affinity chromatography.

偶联:

Unconjugated

产品浓度:

1.1 mg/ml (Please refer to the vial label for the specific concentration.)

保存温度:

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

运输温度:

4°C

预期分子量:

产品形式:

Liquid

存储溶液:

20mM Potassium Phosphate, 150mM NaCl, 0.01% Sodium azide.

生产商:

GeneTex

功能与背景:

Variant histones H2A are synthesized throughout the cell cycle and are very different from classical S-phase regulated H2A. H2AvD is vital for viability, but the exact function of variant histones H2A is not known. H2A is a core component of the nucleosome, an octamer containing two molecules each of H2A, H2B, H3 and H4. The octamer wraps approximately 146 bp of DNA. HsAvD is expressed both maternally and zygotically and is found in embryos through to adults (female only). The human homologue, H2AX, is phosphorylated by ATM protein kinase when double strand DNA breaks occur. In mouse, H2AX "knock out" mice have an increased incidence of cancer.

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