HLA-DQA1 antibody-多抗-深圳欣博盛生物科技有限公司

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HLA-DQA1 antibody

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品牌：GeneTex

官网链接

说明书

折扣/货期

货号：GTX32654

规格：100μl

目录价：￥5000

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

HLA-DQA1 antibody

别名:

major histocompatibility complex, class II, DQ alpha 1 , CELIAC1 , DQ-A1 , DQA1 , HLA-DQA

反应种属:

Human, Mouse

宿主来源:

Rabbit

实验应用:

IHC-P, WB

同种型:

IgG

免疫原:

Recombinant fusion protein containing a sequence corresponding to amino acids 24-216 of human HLA-DQA1 (NP_002113.2).

克隆性:

Polyclonal

克隆号:

纯化方式:

Purified by affinity chromatography

偶联:

Unconjugated

产品浓度:

Batch dependent (Please refer to the vial label for the specific concentration.)

保存温度:

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

运输温度:

4°C

预期分子量:

产品形式:

Liquid

存储溶液:

PBS, 50% Glycerol, 0.02% Sodium azide.

生产商:

GeneTex

功能与背景:

HLA-DQA1 belongs to the HLA class II alpha chain paralogues. The class II molecule is a heterodimer consisting of an alpha (DQA) and a beta chain (DQB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B Lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa. It is encoded by 5 exons; exon 1 encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, and exon 4 encodes the transmembrane domain and the cytoplasmic tail. Within the DQ molecule both the alpha chain and the beta chain contain the polymorphisms specifying the peptide binding specificities, resulting in up to four different molecules. Typing for these polymorphisms is routinely done for bone marrow transplantation. [provided by RefSeq, Jul 2008]

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