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折扣/货期| 货号：GTX638111 | 规格：100μl | 目录价：￥4000 |
| 货号：GTX638111-S | 规格：25μl | 目录价：￥1700 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
HLA-DQA1 antibody [HL2139]
别名:
major histocompatibility complex, class II, DQ alpha 1 , CELIAC1 , DQ-A1 , DQA1 , HLA-DQA
反应种属:
Human
宿主来源:
Rabbit
实验应用:
ICC/IF, WB
靶标/特异性:
This antibody was raised against human HLA-DQA1 Extracellular domain.
同种型:
IgG
免疫原:
Recombinant protein encompassing a sequence within the Extracellular domain of human HLA-DQA1. The exact sequence is proprietary.
克隆性:
Monoclonal
克隆号:
HL2139
纯化方式:
Affinity purified by Protein A.
偶联:
Unconjugated
产品浓度:
1 mg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
产品形式:
Liquid
存储溶液:
PBS, no preservatives.
生产商:
GeneTex
功能与背景:
HLA-DQA1 belongs to the HLA class II alpha chain paralogues. The class II molecule is a heterodimer consisting of an alpha (DQA) and a beta chain (DQB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B Lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa. It is encoded by 5 exons; exon 1 encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, and exon 4 encodes the transmembrane domain and the cytoplasmic tail. Within the DQ molecule both the alpha chain and the beta chain contain the polymorphisms specifying the peptide binding specificities, resulting in up to four different molecules. Typing for these polymorphisms is routinely done for bone marrow transplantation. [provided by RefSeq, Jul 2008]
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