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折扣/货期| 货号：GTX21005 | 规格：50μg | 目录价：￥5000 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
HMW Kininogen antibody [2B5]
别名:
BDK , BK , KNG , KNG1 , kininogen 1
反应种属:
Human
宿主来源:
Mouse
实验应用:
Coagulation assay, ELISA, WB
靶标/特异性:
This antibody recognizes the common heavy chain (~64kDa) of human HMWK and can neutralize the inhibitory activity of HMWK on platelet calpain.
同种型:
IgG1
免疫原:
Purified human high molecular weight kininogen.
克隆性:
Monoclonal
克隆号:
2B5
纯化方式:
Protein G purified
偶联:
Unconjugated
产品浓度:
Batch dependent (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
产品形式:
Liquid
存储溶液:
PBS, no preservatives.
生产商:
GeneTex
功能与背景:
This gene uses alternative splicing to generate two different proteins- high molecular weight kininogen (HMWK) and low molecular weight kininogen (LMWK). HMWK is essential for blood coagulation and assembly of the kallikrein-kinin system. Also, bradykinin, a peptide causing numerous physiological effects, is released from HMWK. Bradykinin also functions as an antimicrobial peptide with antibacterial and antifungal activity. In contrast to HMWK, LMWK is not involved in blood coagulation. Three transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Nov 2014]
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