| 货号:GTX26106 | 规格:50μl | 目录价:¥3700 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
hnRNP L antibody [4D11]
别名:
heterogeneous nuclear ribonucleoprotein L , HNRPL , P/OKcl.14 , hnRNP-L
反应种属:
Bovine, Chicken, Human, Monkey, Mouse, Newt
宿主来源:
Mouse
实验应用:
ELISA, ICC/IF, IP, WB
同种型:
IgG1
免疫原:
hnRNP proteins.
克隆性:
Monoclonal
克隆号:
4D11
纯化方式:
Purified immunoglobulin
偶联:
Unconjugated
产品浓度:
Batch dependent (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
预期分子量:
64
产品形式:
Liquid
存储溶液:
PBS, 15mM Sodium azide.
生产商:
GeneTex
功能与背景:
Heterogeneous nuclear RNAs (hnRNAs) which include mRNA precursors and mature mRNAs are associated with specific proteins to form heterogenous ribonucleoprotein (hnRNP) complexes. Heterogeneous nuclear ribonucleoprotein L is among the proteins that are stably associated with hnRNP complexes and along with other hnRNP proteins is likely to play a major role in the formation, packaging, processing, and function of mRNA. Heterogeneous nuclear ribonucleoprotein L is present in the nucleoplasm as part of the HNRP complex. HNRP proteins have also been identified outside of the nucleoplasm. Exchange of hnRNP for mRNA-binding proteins accompanies transport of mRNA from the nucleus to the cytoplasm. Since HNRP proteins have been shown to shuttle between the nucleus and the cytoplasm, it is possible that they also have cytoplasmic functions.Strucutrally, HNRPL contains 2 segments of approximately 80 amino acids each which are weakly related to each other and to the ribonucleoprotein consensus sequence-type RNA-binding domains of other hnRNP and snRNP proteins.
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