深圳欣博盛生物科技有限公司 a1

HOXB4 Recombinant Protein
品牌:ProSci LLC
货号:92-525 规格:0.05 mg 目录价:¥10494.9
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
HOXB4 Recombinant Protein
别名:
Homeobox protein Hox-B4, Homeobox protein Hox-2.6, Homeobox protein Hox-2F, HOXB4, HOX2F, HOX-2F
表达系统:
E. coli
保存温度:
Store at -20˚C, stable for 6 months after receipt.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
运输温度:
Dry Ice
产品形式:
Liquid
存储溶液:
Supplied as a 0.2 um filtered solution of 4mM HCl. It is not recommended to reconstitute to a concentration less than 100 ug/ml.
产地:
美国
生产商:
Prosci
功能与背景:
Homeobox B4 (HOXB4) is encoded by the HOXB4 gene which is a member of the the class I homeobox (HOX) gene family and encodes a nuclear protein with a homeobox DNA-binding domain. These genes are master control regulators of developmental programs including embryonic and adult hematopoiesis. Multiple HOX genes, including HOXB4, are highly expressed in the hematopoietic stem cells (HSC) compartment. HOXB4 gene can act in opposite ways when expressed by different cells, promoting the proliferation of stem cells whilst activating the apoptotic pathway in some embryonic structures. The protein HOXB4, as a homeodomain transcription factor, has been shown to be an important regulator of stem cell renewal and hematopoiesis. Incellular or ectopic expression of HOXB4 expands hematopoietic stem and progenitor cells in vivo and in vitro, making it a potential candidate for therapeutic stem cell expansion.
纯度:
Greater than 95% as determined by reducing SDS-PAGE.
Endotoxin level less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test.
Accession #:
P17483
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