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折扣/货期| 货号：SPC-195D-A390 | 规格：100 µg | 目录价：￥4246.2 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
HSP110 Antibody: ATTO 390
别名:
Heat shock 105kDa alpha Antibody, heat shock 105kDa beta Antibody, HSP105 Antibody, HSP105A Antibody, HSP105B Antibody, HSP110 Antibody, HSPH1 Antibody, NY CO 25 Antibody
产品描述:
Rabbit Anti-Hamster HSP110 Polyclonal
反应种属:
Human | Mouse | Rat | Bovine | Monkey | Hamster | Sheep | Yeast | Shark | Gummy Shark (Mustelus antarcticus) | School Shark (Galeorhinus galeus)
宿主来源:
Rabbit
实验应用:
WB | IHC | ICC/IF
靶标/特异性:
Detects ~110kDa.
推荐稀释度:
WB (1:1000), IHC (1:100); optimal dilutions for assays should be determined by the user.
免疫原:
Synthetic peptide derived from the sequence of hamster HSP110; sequence identical to human and mouse
免疫原种属:
Hamster
克隆性:
Polyclonal
纯化方式:
Protein A Purified
偶联:
ATTO 390
产品浓度:
1 mg/ml
保存温度:
Conjugated antibodies should be stored according to the product label
运输温度:
Blue Ice or 4ºC
存储溶液:
PBS pH7.2, 50% glycerol, 0.09% sodium azide *Storage buffer may change when conjugated
产地:
加拿大
功能与背景:
HSP110 belongs to a family of large stress proteins known as the HSP110/SSE Family. The proteins in this family are the most distantly known relatives of the well studied HSP70 family. They share 30-33% amino acid identity, mostly in the conserved ATP-binding domain (1). HSP110 cooperates with HSP70 in protein folding in the eukaryotic cytosol (2). In mammals, HSP110 is constitutively expressed, but exhibits particularly high levels in the brain. Both HSP70 and HSP110 are elevated after cerebral ischemia. Recent studies demonstrate that the protective effects of HSP110 deficiency in cerebral ischemia may partly be mediated by an increase in the chaperone activity of HSP70 (3). Studies also suggest that HSP110 can be used in heat shock protein-based cancer immunotherapy (4).
Accession #:
NP_006635.3
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