Human GALE protein, His tag-其他重组蛋白-深圳欣博盛生物科技有限公司

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Human GALE protein, His tag

品牌：GeneTex

官网链接

说明书

折扣/货期

货号：GTX67401-pro

规格：100μg

目录价：￥4000

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

Human GALE protein, His tag

别名:

UDP-galactose-4-epimerase , SDR1E1

克隆号:

偶联:

Unconjugated

产品浓度:

0.5 mg/ml (Please refer to the vial label for the specific concentration.)

表达系统:

E. coli

保存温度:

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

运输温度:

dry ice

产品形式:

Liquid

存储溶液:

20mM Tris-HCl, 100mM NaCl, 10% Glycerol, 5mM DTT, 1mM EDTA, no preservatives.

生产商:

GeneTex

功能与背景:

This gene encodes UDP-galactose-4-epimerase which catalyzes two distinct but analogous reactions: the epimerization of UDP-glucose to UDP-galactose, and the epimerization of UDP-N-acetylglucosamine to UDP-N-acetylgalactosamine. The bifunctional nature of the enzyme has the important metabolic consequence that mutant cells (or individuals) are dependent not only on exogenous galactose, but also on exogenous N-acetylgalactosamine as a necessary precursor for the synthesis of glycoproteins and glycolipids. Mutations in this gene result in epimerase-deficiency galactosemia, also referred to as galactosemia type 3, a disease characterized by liver damage, early-onset cataracts, deafness and cognitive disability, with symptoms ranging from mild ('peripheral' form) to severe ('generalized' form). Multiple alternatively spliced transcripts encoding the same protein have been identified. [provided by RefSeq, Jul 2008]

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