| 货号:GTX68716-pro | 规格:500μl | 目录价:¥4100 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
Human MRI protein, His tag
别名:
apoptotic peptidase activating factor 1 , APAF-1 , CED4
实验应用:
IP
克隆号:
偶联:
Unconjugated
产品浓度:
0.2 mg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store this product at 4ºC, DO NOT FREEZE. The product is stable for one year from the date of shipment.
运输温度:
dry ice
产品形式:
Liquid
存储溶液:
PBS, BSA, 0.1% Sodium azide.
生产商:
GeneTex
功能与背景:
This gene encodes a cytoplasmic protein that initiates apoptosis. This protein contains several copies of the WD-40 domain, a caspase recruitment domain (CARD), and an ATPase domain (NB-ARC). Upon binding cytochrome c and dATP, this protein forms an oligomeric apoptosome. The apoptosome binds and cleaves caspase 9 preproprotein, releasing its mature, activated form. Activated caspase 9 stimulates the subsequent caspase cascade that commits the cell to apoptosis. Alternative splicing results in several transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
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