Human PYGL protein, His tag-其他重组蛋白-深圳欣博盛生物科技有限公司

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Human PYGL protein, His tag

品牌：GeneTex

官网链接

说明书

折扣/货期

货号：GTX67717-pro

规格：10μg

目录价：￥4100

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

Human PYGL protein, His tag

别名:

glycogen phosphorylase L , GSD6

克隆号:

偶联:

Unconjugated

产品浓度:

0.25 mg/ml (Please refer to the vial label for the specific concentration.)

表达系统:

E. coli

保存温度:

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

运输温度:

dry ice

产品形式:

Liquid

存储溶液:

PBS, 30% Glycerol, 1mM DTT, no preservatives.

生产商:

GeneTex

功能与背景:

This gene encodes a homodimeric protein that catalyses the cleavage of alpha-1,4-glucosidic bonds to release glucose-1-phosphate from liver glycogen stores. This protein switches from inactive phosphorylase B to active phosphorylase A by phosphorylation of serine residue 15. Activity of this enzyme is further regulated by multiple allosteric effectors and hormonal controls. Humans have three glycogen phosphorylase genes that encode distinct isozymes that are primarily expressed in liver, brain and muscle, respectively. The liver isozyme serves the glycemic demands of the body in general while the brain and muscle isozymes supply just those tissues. In glycogen storage disease type VI, also known as Hers disease, mutations in liver glycogen phosphorylase inhibit the conversion of glycogen to glucose and results in moderate hypoglycemia, mild ketosis, growth retardation and hepatomegaly. Alternative splicing results in multiple transcript variants encoding different isoforms.[provided by RefSeq, Feb 2011]

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