Human Recombinant Transthyretin L55P Variant Protein Filaments-其他重组蛋白-深圳欣博盛生物科技有限公司

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Human Recombinant Transthyretin L55P Variant Protein Filaments

品牌：Stressmarq

官网链接

说明书

折扣/货期

货号：SPR-464E

规格：100 µg x5

目录价：￥20664

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

Human Recombinant Transthyretin L55P Variant Protein Filaments

别名:

Amyloid polyneuropathy Protein, Amyloidosis I Protein, ATTR Protein, Carpal tunnel syndrome 1 Protein, CTS Protein, CTS1 Protein, HEL111 Protein, HsT2651 Protein, PALB Protein, Prealbumin Protein, Prealbumin amyloidosis type I Protein, Prealbumin Thyroxine-binding Protein, TBPA Protein, Thyroxine binding prealbumin Protein, Transthyretin Protein, TTHY_HUMAN Protein,TTR Protein

产品描述:

Human Recombinant Transthyretin L55P Variant Protein Filaments

反应种属:

Human

实验应用:

WB | SDS-PAGE | In vivo assay | In vitro assay

纯化方式:

Ion-exchange Purified

偶联:

No Tag

产品浓度:

Lot/batch specific. See included datasheet.

表达系统:

E. coli

保存温度:

-80ºC

运输温度:

Dry Ice. Shipping note: Product will be shipped separately from other products purchased in the same order.

预期分子量:

13.876 kDa

存储溶液:

PBS pH 7.4

产地:

加拿大

功能与背景:

Transthyretin is a transport protein in the serum and cerebospinal fluid that carried the thyroid hormone Thyroxine and retinol-binding protein bound to retinol. TTR misfolding and aggregation is known to be associated with the amyloiddiseases SSA, FAP and FAC (1-5). TTR is also thought to have beneficial side effects, such as binding to beta-amyloid protein, preventing beta-amyloid from accumulating into the plaques associated with Alzheimer's Disease (6). The L55P variant TTR is distinct from the other variants in that the L55P tetramer can dissociate to the monomeric amyloidogenic intermediate and form fibril precursors (7).

纯度:

>95%

Accession #:

NP_000362.1