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折扣/货期| 货号：SPR-451E | 规格：100 µg x5 | 目录价：￥20223 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Human Recombinant Transthyretin L55P Variant Protein Monomers
别名:
Amyloid polyneuropathy Protein Monomer, Amyloidosis I Protein Monomer, ATTR Protein Monomer, Carpal tunnel syndrome 1 Protein Monomer, CTS Protein Monomer, CTS1 Protein Monomer,= HEL111 Protein Monomer, HsT2651 Protein Monomer, PALB Protein Monomer, Prealbumin Protein Monomer, Prealbumin amyloidosis type I Protein Monomer, Prealbumin Thyroxine-binding Protein Monomer, TBPA Protein Monomer, Thyroxine binding prealbumin Protein Monomer, Transthyretin Protein Monomer, TTHY_HUMAN Protein Monomer,TTR Protein Monomer, TTR protein
产品描述:
Human Recombinant Transthyretin L55P Variant Protein Monomers
反应种属:
Human
实验应用:
WB | SDS-PAGE | In vivo assay | In vitro assay
纯化方式:
Ion-exchange Purified
偶联:
No tag
产品浓度:
Lot/batch specific. See included datasheet.
表达系统:
E. coli
保存温度:
-80ºC
运输温度:
Dry Ice. Shipping note: Product will be shipped separately from other products purchased in the same order.
预期分子量:
13.876 kDa
存储溶液:
PBS pH 7.4
产地:
加拿大
功能与背景:
Transthyretin is a transport protein in the serum and cerebospinal fluid that carried the thyroid hormone Thyroxine and retinol-binding protein bound to retinol. TTR misfolding and aggregation is known to be associated with the amyloiddiseases SSA, FAP and FAC (1-5). TTR is also thought to have beneficial side effects, such as binding to beta-amyloid protein, preventing beta-amyloid from accumulating into the plaques associated with Alzheimer's Disease (6). The L55P variant TTR is distinct from the other variants in that the L55P tetramer can dissociate to the monomeric amyloidogenic intermediate and form fibril precursors (7).
纯度:
>95%
Accession #:
NP_000362.1
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下一个:Human Recombinant Transthyretin Y78F Variant Protein Monomers
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