Human Recombinant Transthyretin Y78F Variant Protein Filaments-其他重组蛋白-深圳欣博盛生物科技有限公司

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Human Recombinant Transthyretin Y78F Variant Protein Filaments

品牌：Stressmarq

官网链接

说明书

折扣/货期

货号：SPR-465E

规格：100 µg x5

目录价：￥20664

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

Human Recombinant Transthyretin Y78F Variant Protein Filaments

别名:

Amyloid polyneuropathy Protein, Amyloidosis I Protein, ATTR Protein, Carpal tunnel syndrome 1 Protein, CTS Protein, CTS1 Protein, HEL111 Protein, HsT2651 Protein, PALB Protein, Prealbumin Protein, Prealbumin amyloidosis type I Protein, Prealbumin Thyroxine-binding Protein, TBPA Protein, Thyroxine binding prealbumin Protein, Transthyretin Protein, TTHY_HUMAN Protein,TTR Protein

产品描述:

Human Recombinant Transthyretin Y78F Variant Protein Filaments

反应种属:

Human

实验应用:

WB | SDS-PAGE | In vivo assay | In vitro assay

纯化方式:

Ion-exchange Purified

偶联:

No Tag

产品浓度:

Lot/batch specific. See included datasheet.

表达系统:

E. coli

保存温度:

-80ºC

运输温度:

Dry Ice. Shipping note: Product will be shipped separately from other products purchased in the same order.

预期分子量:

13.876 kDa

存储溶液:

PBS pH 7.4

产地:

加拿大

功能与背景:

Transthyretin is a transport protein in the serum and cerebospinal fluid that carried the thyroid hormone Thyroxine and retinol-binding protein bound to retinol. TTR misfolding and aggregation is known to be associated with the amyloiddiseases SSA, FAP and FAC (1-5). TTR is also thought to have beneficial side effects, such as binding to beta-amyloid protein, preventing beta-amyloid from accumulating into the plaques associated with Alzheimer's Disease (6). The mutant variant Y78F indicates a destabilization of the contacts between the alpha-helix and AB loop and the body of the molecule, potentially leading to applications in immne therapy for FAP (7).

纯度:

>95%

Accession #:

NP_000362.1

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