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折扣/货期| 货号：SPR-452E | 规格：100 µg x5 | 目录价：￥20223 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Human Recombinant Transthyretin Y78F Variant Protein Monomers
别名:
Amyloid polyneuropathy Protein Monomer, Amyloidosis I Protein Monomer, ATTR Protein Monomer, Carpal tunnel syndrome 1 Protein Monomer, CTS Protein Monomer, CTS1 Protein Monomer,= HEL111 Protein Monomer, HsT2651 Protein Monomer, PALB Protein Monomer, Prealbumin Protein Monomer, Prealbumin amyloidosis type I Protein Monomer, Prealbumin Thyroxine-binding Protein Monomer, TBPA Protein Monomer, Thyroxine binding prealbumin Protein Monomer, Transthyretin Protein Monomer, TTHY_HUMAN Protein Monomer,TTR Protein Monomer, TTR protein
产品描述:
Human Recombinant Transthyretin Y78F Variant Protein Monomers
反应种属:
Human
实验应用:
WB | SDS-PAGE | In vivo assay | In vitro assay
纯化方式:
Ion-exchange Purified
偶联:
No tag
产品浓度:
Lot/batch specific. See included datasheet.
表达系统:
E. coli
保存温度:
-80ºC
运输温度:
Dry Ice. Shipping note: Product will be shipped separately from other products purchased in the same order.
预期分子量:
13.876 kDa
存储溶液:
PBS pH 7.4
产地:
加拿大
功能与背景:
Transthyretin is a transport protein in the serum and cerebospinal fluid that carried the thyroid hormone Thyroxine and retinol-binding protein bound to retinol. TTR misfolding and aggregation is known to be associated with the amyloiddiseases SSA, FAP and FAC (1-5). TTR is also thought to have beneficial side effects, such as binding to beta-amyloid protein, preventing beta-amyloid from accumulating into the plaques associated with Alzheimer's Disease (6). The mutant variant Y78F indicates a destabilization of the contacts between the alpha-helix and AB loop and the body of the molecule, potentially leading to applications in immne therapy for FAP (7).
纯度:
>95%
Accession #:
NP_000362.1
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