Human TGF beta 2 protein, His tag (active)-细胞因子、趋化因子与生长因子-深圳欣博盛生物科技有限公司

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Human TGF beta 2 protein, His tag (active)

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品牌：GeneTex

官网链接

说明书

折扣/货期

货号：GTX00211-pro

规格：10μg

目录价：￥4000

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

Human TGF beta 2 protein, His tag (active)

别名:

transforming growth factor beta 2 , G-TSF , LDS4 , TGF-beta2

实验应用:

Functional Assay

克隆号:

偶联:

Unconjugated

产品浓度:

表达系统:

E. coli

保存温度:

For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, store at -20ºC or below. After reconstitution, keep as concentrated solution. Avoid freeze-thaw cycles.

运输温度:

4°C

产品形式:

Lyophilized powder

存储溶液:

Reconstitute with 20mM Tris and 150mM NaCl to 0.1-1.0mg/ml. Do not vortex. Lyophilized from 20mM Tris, 150mM NaCl, 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose, ProClin 300.

生产商:

GeneTex

功能与背景:

This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate a latency-associated peptide (LAP) and a mature peptide, and is found in either a latent form composed of a mature peptide homodimer, a LAP homodimer, and a latent TGF-beta binding protein, or in an active form consisting solely of the mature peptide homodimer. The mature peptide may also form heterodimers with other TGF-beta family members. Disruption of the TGF-beta/SMAD pathway has been implicated in a variety of human cancers. A chromosomal translocation that includes this gene is associated with Peters' anomaly, a congenital defect of the anterior chamber of the eye. Mutations in this gene may be associated with Loeys-Dietz syndrome. This gene encodes multiple isoforms that may undergo similar proteolytic processing. [provided by RefSeq, Aug 2016]

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