货号:SYN-3033-M001 | 规格:1 mg | 目录价:¥1204 |
货号:SYN-3033-M005 | 规格:5 mg | 目录价:¥1820 |
货号:SYN-3033-M010 | 规格:10 mg | 目录价:¥2422 |
货号:SYN-3033-M050 | 规格:50 mg | 目录价:¥6804 |
货号:SYN-3033-M100 | 规格:100 mg | 目录价:¥询价 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
I-BET762
别名:
GSK-525762A
产品描述:
I-BET762 (GSK525762A) is an inhibitor for BET (bromodomain and extra terminal domain) proteins, BRD2, BRD3 and BRD4. It binds to the tandem bromodomains of BET with a Kd of 50.5-61.3nM, displaces a tetra-acetylated H4 peptide prebound to tandem bromodomains of BET with IC50 of 32.5-42.5nM in FRET analysis. I-BET762 disrupts the formation of the chromatin complexes essential for expression of inflammatory genes.
保存温度:
+4°C
运输温度:
Ambient
预期分子量:
423.9
产品形式:
solid
有效期:
Stable for at least 2 years after receipt when stored at -20°C.
产地:
瑞士
纯度:
>95%
CAS号:
1260907-17-2
分子式:
C22H22ClN5O2
溶解度:
Soluble in DMSO.
促销活动
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