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折扣/货期| 货号：GTX16890 | 规格：50μg | 目录价：￥5600 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
IGF1R alpha + beta antibody [alphaIR3]
别名:
insulin like growth factor 1 receptor , CD221 , IGFIR , IGFR , JTK13
反应种属:
Human
宿主来源:
Mouse
实验应用:
ICC/IF, IP, Neutralizing/Inhibition
靶标/特异性:
This antibody recognizes the ~130 kDa α and the ~90 kDa β subunits of IGF-I receptor and is not suitable for use in IHC-P or WB.
同种型:
IgG1
免疫原:
Immunogen used was partially purified receptor from human placenta.
克隆性:
Monoclonal
克隆号:
alphaIR3
纯化方式:
Affinity purified with antigen
偶联:
Unconjugated
产品浓度:
0.1 mg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.
运输温度:
4°C
产品形式:
Liquid
存储溶液:
0.05M Sodium Phosphate buffer, 0.2% Gelatin, 0.1% Sodium azide.
生产商:
GeneTex
功能与背景:
This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, May 2014]
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