IGF1R beta (phospho Tyr1131) / Insulin Receptor beta (phospho Tyr1146) antibody-多抗-深圳欣博盛生物科技有限公司

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IGF1R beta (phospho Tyr1131) / Insulin Receptor beta (phospho Tyr1146) antibody

品牌：GeneTex

官网链接

说明书

折扣/货期

货号：GTX52315

规格：100μg

目录价：￥5300

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

IGF1R beta (phospho Tyr1131) / Insulin Receptor beta (phospho Tyr1146) antibody

别名:

insulin like growth factor 1 receptor , CD221 , IGFIR , IGFR , JTK13

反应种属:

Human, Mouse, Rat

宿主来源:

Rabbit

实验应用:

IHC, IP, WB

靶标/特异性:

Tyr1161 in full-length IGF-1R is equivalent toTyr1131 in signal peptide cleaved IGF1R, and Tyr1185 in full-length Insulin Receptor is equivalent to Tyr1146 in signal peptide cleaved Insulin Receptor.

同种型:

IgG

免疫原:

A synthesized peptide derived from human IGF1R around the phosphorylation site of Tyr1161, which is equivalent to Tyrosine 1131 in signal peptide cleaved IGF1R.

克隆性:

Polyclonal

克隆号:

纯化方式:

Antigen affinity purification

偶联:

Unconjugated

产品浓度:

1 mg/ml (Please refer to the vial label for the specific concentration.)

保存温度:

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

运输温度:

4°C

产品形式:

Liquid

存储溶液:

PBS, 150mM NaCl, 50% Glycerol, 0.02% Sodium azide.

生产商:

GeneTex

功能与背景:

This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, May 2014]

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